CoPS : Comprehensive Peptide Signature Database

Description:

Comprehensive Peptide Signature Database is an extensive database of 3360 signature peptides, varying in length between 8 to 46 amino acids, representing over 300 functional classes. It provides collating information on the mutation effects on these signature peptides from the Protein Mutant Database (PMD) and identifies the peptide signature(s) occurring in a given biochemical pathway. CoPS provides collating information about these signature peptides from other motifs (eg. PROSITE, BLOCKS, PRINTS), domains (eg. ProDom) & family (eg. COGs) databases. The software is used for

• Functional Assignment to still unknown proteins using 3360 Functional Signatures
• Identification of critical residues in proteins through these signatures using mutation information
• Identification of folding nucleus or structural determinants of the proteins
• Studying protein interactions through these Functional Signatures

Citation

Prakash T., Khandelwal M., Dasgupta D., Dash D. and Brahmachari S. K. (2004) CoPS: Comprehensive peptide signature database^a. Bioinformatics, 20(16), 2886-2888.